Article
[Anticoagulant action and safety of warfarin dosing based on pharmacogenetic testing: results of the first Russian prospective pilot study].
Kardiologiia - 1 Jan 2010
Sychev D A, Antonov I M, Ignat'ev I V, Naumova Iu V, Dmitriev V A, Kropacheva E S, Dobrovol'skiĭ O B, Panchenko E P, Tashenova I A, Kukes V G
Abstract excerpt
Aim of the study was to compare numbers of episodes of excess hypocoagulation and bleeding with warfarin dosing based on pharmacogenetic testing and traditional method in patients with high risk of thromboembolic complications. In 76 patients (43 men and 33 women aged 60.3 +/- 12.3 years) warfarin was administered starting with the dose calculated according to the gage algorithm with consideration of results of...
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