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Article

Mechanisms of type I and type II pseudohypoaldosteronism.

Journal of the American Society of Nephrology : JASN - 1 Nov 2010

Furgeson Seth B, Linas Stuart

Abstract excerpt

Pseudohypoaldosteronism (PHA) types I and II are curious genetic disorders that share hyperkalemia as a predominant finding. Together they have become windows to understanding new molecular physiology in the kidney. Autosomal recessive PHAI results from mutations in the epithelial sodium channel (ENaC), whereas autosomal dominant PHAI is characterized by mutations in the mineralocorticoid receptor. PHAII is the...

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Share to Epithelial Sodium Channels
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to WNK Lysine-Deficient Protein Kinase 1

Source

Identifiers

PMID: 20829405
DOI: 10.1681/ASN.2010050457

Genes

WNK4
WNK1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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