Article
Classification of pseudohypoaldosteronism type II as type IV renal tubular acidosis: results of a literature review.
Endocrine journal - 28 Jul 2023
Adachi Masanori, Motegi Sakura, Nagahara Keiko, Ochi Ayako, Toyoda Junya, Mizuno Katsumi
Abstract excerpt
Pseudohypoaldosteronism (PHA) type II (PHA2) is a genetic disorder that leads to volume overload and hyperkalemic metabolic acidosis. PHA2 and PHA type I (PHA1) have been considered to be genetic and pediatric counterparts to type IV renal tubular acidosis (RTA). Type IV RTA is frequently found in adults with chronic kidney disease and is characterized by hyperchloremic hyperkalemic acidosis with normal anion gap...
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