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Article

Dynamics of telomere's length and telomerase activity in Philadelphia chromosome negative myeloproliferative neoplasms.

Leukemia research - 1 Apr 2011

Spanoudakis Emmanouil, Bazdiara Ioanna, Pantelidou Despoina, Kotsianidis Ioannis, Papadopoulos Vasilios, Margaritis Dimitrios, Xanthopoulidis George, Moustakidis Eleftherios, Mantzourani Stamatia, Bourikas George, Tsatalas Costas

Abstract excerpt

Telomere exhaustion and increased telomerase activity are associated with the acquisition of aggressive molecular events in a variety of haematological malignancies. In Philadelphia chromosome negative myeloproliferative neoplasms (Ph(neg)MPN's), telomere dynamics during clonal evolution of these diseases have not yet been fully elucidated. Herein we demonstrated that telomere shortening is a global phenomenon in...

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Identifiers

PMID: 20828816
DOI: 10.1016/j.leukres.2010.07.042

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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