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Article

The perilipin homologue, lipid storage droplet 2, regulates sleep homeostasis and prevents learning impairments following sleep loss.

PLoS biology - 31 Aug 2010

Thimgan Matthew S, Suzuki Yasuko, Seugnet Laurent, Gottschalk Laura, Shaw Paul J

Abstract excerpt

Extended periods of waking result in physiological impairments in humans, rats, and flies. Sleep homeostasis, the increase in sleep observed following sleep loss, is believed to counter the negative effects of prolonged waking by restoring vital biological processes that are degraded during sleep deprivation. Sleep homeostasis, as with other behaviors, is influenced by both genes and environment. We report here...

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Identifiers

PMID: 20824166
DOI: 10.1371/journal.pbio.1000466
PMCID: PMC2930866

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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