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Article

Multinucleated giant cells with an osteoclast phenotype derived from caprine peripheral blood mononuclear cells.

Veterinary journal (London, England : 1997) - 1 Sept 2011

Pisoni Giuliano, D'Amelio Patrizia, Sassi Francesca, Manarolla Giovanni, Scaccabarozzi Licia, Locatelli Clara, Mazzocchi Nausicaa, Baruscotti Mirko, DiFrancesco Dario, Moroni Paolo

Abstract excerpt

Formation of multinucleated giant cells (MGCs) by macrophage fusion is a typical cytopathic effect of lentiviral replication in caprine monocytes and MGC formation from cultured caprine peripheral blood mononuclear cells (PBMCs) has been considered to be diagnostic for small ruminant lentivirus (SRLV) infection. In this study, formation of MGCs was observed after 7-14 days when PBMCs were cultured from healthy...

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PMID: 20822938
DOI: 10.1016/j.tvjl.2010.07.016

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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