Article
All-or-none craniorachischisis in Loop-tail mutant mouse chimeras.
Development (Cambridge, England) - 1 Sept 1990
Musci T S, Mullen R J
Abstract excerpt
Mouse embryos homozygous for the mutant gene Loop-tail (Lp) are characterized by craniorachischisis, an open neural tube extending from the midbrain to the tail. In the present study, experimental chimeric mice containing mixtures of genetically mutant (from Lp/+ x Lp/+ matings) and genetically n...
Topics
- Animals
- Central Nervous System
- Chimera
- Gene Expression
- Mice
- Mice, Inbred Strains
- Mice, Mutant Strains
- Neural Tube Defects
- Phenotype