Article
Molecular testing on bronchial washings for the diagnosis and predictive assessment of lung cancer.
Molecular oncology - 1 Sept 2020
Roncarati Roberta, Lupini Laura, Miotto Elena, Saccenti Elena, Mascetti Susanna, Morandi Luca, Bassi Cristian, Rasio Debora, Callegari Elisa, Conti Valentina, Rinaldi Rosa, Lanza Giovanni, Gafà Roberta, Papi Alberto, Frassoldati Antonio, Sabbioni Silvia, Ravenna Franco, Casoni Gian L, Negrini Massimo
Abstract excerpt
Cytopathological analyses of bronchial washings (BWs) collected during fibre-optic bronchoscopy are often inconclusive for lung cancer diagnosis. To address this issue, we assessed the suitability of conducting molecular analyses on BWs, with the aim to improve the diagnosis and outcome prediction of lung cancer. The methylation status of RASSF1A, CDH1, DLC1 and PRPH was analysed in BW samples from 91 lung cancer...
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