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Article

Palladin, an actin-associated protein, is required for adherens junction formation and intercellular adhesion in HCT116 colorectal cancer cells.

International journal of oncology - 1 Oct 2010

Tay Puei Nam, Tan Patrick, Lan Yuhong, Leung Carol Ho-Wing, Laban Mirtha, Tan Tze Chin, Ni Hongmin, Manikandan Jayapal, Rashid Suhaimi Bin Abdul, Yan Benedict, Yap Celestial Therese, Lim Lina Hsiu Kim, Lim Yaw Chyn, Hooi Shing Chuan

Abstract excerpt

Palladin is a scaffold protein involved in the formation of actin-associated protein complexes. Gene expression array analysis on the poorly metastatic HCT116 colon cancer cell line and a metastatic derivative cell line (E1) with EMT (epithelial-mesenchymal transition) features showed a down-regu...

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Source

Identifiers

PMID: 20811713
DOI: 10.3892/ijo_00000742

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20811713-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

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Click a neighbor to travelStep 1 · 12 closest

Palladin, an actin-associated protein, is required for adherens junction formation and intercellular adhesion in HCT116 colorectal cancer cells.PMID 20811713Read ↗

The role of palladin in actin organization and cell motility.Semantic proximity Read ↗

Alterations of the apical junctional complex and actin cytoskeleton and their role in colorectal cancer progressionSemantic proximity Read ↗

Disruption of palladin results in neural tube closure defects in mice.Semantic proximity Read ↗

Expression changes of cell-cell adhesion-related genes in colorectal tumorsSemantic proximity Read ↗

Disrupted interaction between CFTR and AF-6/afadin aggravates malignant phenotypes of colon cancer.Semantic proximity Read ↗

mDia2 formin selectively interacts with catenins and not E-cadherin to regulate Adherens Junction formationSemantic proximity Read ↗

Subcellular distribution and expression of cofilin and ezrin in human colon adenocarcinoma cell lines with different metastatic potentialSemantic proximity Read ↗

The leukocyte protein L-plastin induces proliferation, invasion and loss of E-cadherin expression in colon cancer cells.Semantic proximity Read ↗

Podoplanin-mediated platelet activation promotes proliferation and invasion of colon cancer cellsSemantic proximity Read ↗

The actin-bundling protein palladin is an Akt1-specific substrate that regulates breast cancer cell migration.Semantic proximity Read ↗

The Transcription Factor Snail Induces Tumor Cell Invasion through Modulation of the Epithelial Cell Differentiation ProgramSemantic proximity Read ↗

DCC regulates cell adhesion in human colon cancer derived HT-29 cells and associates with ezrinSemantic proximity Read ↗

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