Article
Detection of M2-macrophages in uveal melanoma and relation with survival.
Investigative ophthalmology & visual science - 3 Feb 2011
Bronkhorst Inge H G, Ly Long V, Jordanova Ekaterina S, Vrolijk Johannes, Versluis Mieke, Luyten Gregorius P M, Jager Martine J
Abstract excerpt
PURPOSE: The presence of a high number of infiltrating macrophages in uveal melanoma is associated with a bad prognosis. However, there are several known types of macrophages, of which the M2 is considered to be proangiogenic and tumor-promoting. This study was conducted to determine whether the tumor-infiltrating macrophages in uveal melanoma are of this M2 subtype. METHODS: Macrophages were identified in...
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