Article
Inflammatory cell infiltrates in advanced metastatic uveal melanoma.
Human pathology - 1 Aug 2017
Krishna Yamini, McCarthy Conni, Kalirai Helen, Coupland Sarah E
Abstract excerpt
Current treatments for metastatic uveal melanoma (mUM) are limited and rarely prolong patient survival. Immunotherapy trials for mUM are few and to date have demonstrated only marginal success. High densities of tumor-associated macrophages (TAMs) and infiltrating T lymphocytes (TILs) in primary UM are associated with poor prognosis. Little is known about the immune microenvironment of mUM. Our aim was to examine...
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