Article
Detection and functional evaluation of -262A/T and -188A/G polymorphisms of SLAM gene in patients with systemic lupus erythematosus.
The Journal of rheumatology - 1 Nov 2010
You Yi, Wang Zhe, Deng Guo-Hong, Liu Yi, Hao Fei
Abstract excerpt
OBJECTIVE: Signaling lymphocytic activation molecule (SLAM) has been related to the pathology of systemic lupus erythematosus (SLE) through regulation of T cell-dependent humoral immune responses. We investigated the functional associations of the -262A/T and -188A/G polymorphisms of SLAM in Chinese patients with SLE. METHODS: Genotyping of -262A/T (rs2295614) and -188A/G (rs2295613) in SLAM was carried out in...
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