Article
APRIL gene polymorphism and serum sAPRIL levels in children with systemic lupus erythematosus.
Clinical rheumatology - 1 Apr 2017
Namazi Shideh, Tajik Nader, Ziaee Vahid, Sadr Maryam, Soltani Samaneh, Rezaei Arezou, Zoghi Samaneh, Rezaei Nima
Abstract excerpt
Systemic lupus erythematosus (SLE) is a multi-factor autoimmune disorder with diverse clinical manifestations and unclear pathogenesis. Genetic components play important roles in the incidence and development of SLE. Among these, APRIL as a cytokine has roles in the stimulation and antibody production in B cells. APRIL was hypothesized to be associated with SLE. The aim of this study was to assess the involvement...
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