Article
Association of Matrix Metalloproteinase-9 (MMP9) Variants with Primary Angle Closure and Primary Angle Closure Glaucoma.
PloS one - 1 Jan 2016
Chen Xueli, Chen Yuhong, Wiggs Janey L, Pasquale Louis R, Sun Xinghuai, Fan Bao Jian
Abstract excerpt
Shorter axial length observed in patients with primary angle closure glaucoma (PACG) might be due to altered matrix metalloproteinase-9 (MMP9) activity resulting in ECM remodeling during eye growth and development. This study aimed to evaluate common variants in MMP9 for association with PACG. Six tag SNPs of MMP9 were genotyped in a Chinese sample of 1,030 cases, including 572 PACG and 458 primary angle closure...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
