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Article

Genetics and genetic testing in hemolytic uremic syndrome/thrombotic thrombocytopenic purpura.

Seminars in nephrology - 1 Jul 2010

Noris Marina, Remuzzi Giuseppe

Abstract excerpt

The hemolytic uremic syndrome (HUS) and thrombotic thrombocytopenic purpura (TTP) are rare diseases that manifest with thrombocytopenia and microangiopathic hemolytic anemia accompanied by renal and neurologic dysfunction. Most childhood cases of HUS are caused by Shiga-toxin-producing bacteria and have a good prognosis. The other form, atypical HUS (aHUS), accounts for 10% of cases. Prognosis of aHUS and TTP has...

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Identifiers

PMID: 20807612
DOI: 10.1016/j.semnephrol.2010.06.006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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