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Article

T-cell acute lymphoblastic leukemia in association with Börjeson-Forssman-Lehmann syndrome due to a mutation in PHF6.

Pediatric blood & cancer - 1 Oct 2010

Chao Mwe Mwe, Todd Matthew A, Kontny Udo, Neas Katherine, Sullivan Michael J, Hunter Alasdair G, Picketts David J, Kratz Christian P

Abstract excerpt

Börjeson-Forssman-Lehmann syndrome (BFLS) is a rare X-linked mental retardation syndrome that is caused by germline mutations in PHF6. We describe a 9-year-old male with BFLS, who developed T-cell acute lymphoblastic leukemia (T-ALL). The PHF6 gene is located on the X chromosome and encodes a pro...

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Identifiers

PMID: 20806366
DOI: 10.1002/pbc.22574
PMCID: PMC2933084

Genes

PHF6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20806366-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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