Article
Expression levels of uridine 5'-diphospho-glucuronosyltransferase genes in breast tissue from healthy women are associated with mammographic density.
Breast cancer research : BCR - 1 Jan 2010
Haakensen Vilde D, Biong Margarethe, Lingjærde Ole Christian, Holmen Marit Muri, Frantzen Jan Ole, Chen Ying, Navjord Dina, Romundstad Linda, Lüders Torben, Bukholm Ida K, Solvang Hiroko K, Kristensen Vessela N, Ursin Giske, Børresen-Dale Anne-Lise, Helland Aslaug
Abstract excerpt
INTRODUCTION: Mammographic density (MD), as assessed from film screen mammograms, is determined by the relative content of adipose, connective and epithelial tissue in the female breast. In epidemiological studies, a high percentage of MD confers a four to six fold risk elevation of developing breast cancer, even after adjustment for other known breast cancer risk factors. However, the biologic correlates of...
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