Article
The association between ATM D1853N polymorphism and breast cancer susceptibility: a meta-analysis.
Journal of experimental & clinical cancer research : CR - 27 Aug 2010
Gao Lin-Bo, Pan Xin-Min, Sun Hong, Wang Xia, Rao Li, Li Li-Juan, Liang Wei-Bo, Lv Mei-Li, Yang Wen-Zhong, Zhang Lin
Abstract excerpt
BACKGROUND: Emerging evidence suggests that ataxia telangiectasia-mutated (ATM) is involved in numerous damage repair signaling pathways and cell-cycle checkpoints. Heterozygous carriers of ATM-mutations have an increased risk for the development of breast cancer. The purpose of this study is to evaluate the association between ATM exon39 5557G > A (D1853N, rs1801516) polymorphism and breast cancer susceptibility...
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