Article
Association of genetic polymorphisms in STAT1 gene with increased risk of hepatocellular carcinoma.
Oncology - 1 Jan 2010
Zhu Zhong-Zheng, Di Jian-Zhong, Gu Wen-Ye, Cong Wen-Ming, Gawron Andrew, Wang Yu, Zheng Qi, Wang Ai-Zhong, Zhu Guanshan, Zhang Pin, Hou Lifang
Abstract excerpt
OBJECTIVE: Although signal transducer and activator of transcription 1 (STAT1), a transcription factor, plays a critical role in carcinogenesis and has been implicated as a tumor suppressor, few studies have investigated the associations between polymorphisms of this gene and the risk of cancer development. The aim of this study was to examine whether STAT1 gene polymorphisms are associated with the risk of...
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