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Article

Association of genetic polymorphisms in STAT1 gene with increased risk of hepatocellular carcinoma.

Oncology - 1 Jan 2010

Zhu Zhong-Zheng, Di Jian-Zhong, Gu Wen-Ye, Cong Wen-Ming, Gawron Andrew, Wang Yu, Zheng Qi, Wang Ai-Zhong, Zhu Guanshan, Zhang Pin, Hou Lifang

Abstract excerpt

OBJECTIVE: Although signal transducer and activator of transcription 1 (STAT1), a transcription factor, plays a critical role in carcinogenesis and has been implicated as a tumor suppressor, few studies have investigated the associations between polymorphisms of this gene and the risk of cancer d...

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Source

Identifiers

PMID: 20798561
DOI: 10.1159/000320521

Genes

STAT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20798561-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

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Association of genetic polymorphisms in STAT1 gene with increased risk of hepatocellular carcinoma.PMID 20798561Read ↗

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Genetic variants in STAT4 and their interactions with environmental factors for the incidence of hepatocellular carcinoma.Semantic proximity Read ↗

The effects of the interactions of STAT4 rs7574865 with HBV mutations on the risk of hepatocellular carcinoma.Semantic proximity Read ↗

Association of Single Nucleotide Polymorphism rs1053004 in Signal Transducer and Activator of Transcription 3 (STAT3) with Susceptibility to Hepatocellular Carcinoma in Thai Patients with Chronic Hepatitis B.Semantic proximity Read ↗

Single Nucleotide Polymorphisms in STAT3 and STAT4 and Risk of Hepatocellular Carcinoma in Thai Patients with Chronic Hepatitis B.Semantic proximity Read ↗

STAT4 gene polymorphism and risk of chronic hepatitis B-induced hepatocellular carcinoma.Semantic proximity Read ↗

Association between STAT3 polymorphisms and cancer risk: a meta-analysis.Semantic proximity Read ↗

Association of STAT4 polymorphisms with susceptibility to type-1 autoimmune hepatitis in the Japanese population.Semantic proximity Read ↗

STAT3 and STAT5b polymorphism contributes to breast cancer risk and clinical outcomes.Semantic proximity Read ↗

STAT3 gene polymorphisms and susceptibility to non-small cell lung cancer.Semantic proximity Read ↗

Replication of genome wide association studies on hepatocellular carcinoma susceptibility loci of STAT4 and HLA-DQ in a Korean population.Semantic proximity Read ↗

Differential promoter activities of functional haplotypes in the 5'-flanking region of human sulfotransferase 1A1.Semantic proximity Read ↗

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