Article
Gender-specific reduction of estrogen-sensitive small RNA, miR-30b, in subjects with schizophrenia.
Schizophrenia bulletin - 1 May 2012
Mellios Nikolaos, Galdzicka Marzena, Ginns Edward, Baker Stephen P, Rogaev Evgeny, Xu Jun, Akbarian Schahram
Abstract excerpt
Estrogen signaling pathways affect cortical function and metabolism, are thought to play a role in the pathophysiology of schizophrenia, and exert neuroprotective effects in female subjects at risk. However, the molecular signatures of estrogen signaling in normal and diseased cerebral cortex remain largely unexplored. Expression of the estrogen-sensitive small RNA, microRNA-30b (miR-30b), was studied in 30...
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