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Article

Analyses of variants located in estrogen metabolism genes (ESR1, ESR2, COMT and APOE) and schizophrenia.

Schizophrenia research - 1 Mar 2008

Martorell Lourdes, Costas Javier, Valero Joaquín, Gutierrez-Zotes Alfonso, Phillips Christopher, Torres María, Brunet Anna, Garrido Gemma, Carracedo Angel, Guillamat Roser, Vallès Vicenç, Guitart Miriam, Labad Antonio, Vilella Elisabet

Abstract excerpt

Relationships between gender, age-of-onset of schizophrenia and reproductive age strongly suggest a key role for gonadal hormones, and more specifically for estrogens, in the etiology of the illness. Also, estrogens act as neural growth and trophic factors influencing neuron and glial cells in ma...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18164902
DOI: 10.1016/j.schres.2007.11.001

Genes

APOE
COMT
ESR1
ESR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-18164902-2026-09-04.1. Manifest publication-graph-cohort-2026-09-04.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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