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Article

Combination of polymorphisms within the HDAC1 and HDAC3 gene predict tumor recurrence in hepatocellular carcinoma patients that have undergone transplant therapy.

Clinical chemistry and laboratory medicine - 1 Dec 2010

Yang Zhe, Zhou Lin, Wu Li-Ming, Xie Hai-Yang, Zhang Feng, Zheng Shu-Sen

Abstract excerpt

BACKGROUND: Histone deacetylases (HDACs) have been reported to be poor prognostic indicators in patients with cancer. However, no data are available for the role of single nucleotide polymorphism (SNP) of class I HDAC in hepato-cellular carcinoma (HCC). Therefore, we investigated the association of class I HDAC isoforms genomic polymorphisms with risk of HCC and tumor recurrence following liver transplantation...

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Source

Identifiers

PMID: 20731616
DOI: 10.1515/CCLM.2010.353

Genes

HDAC1
HDAC3
HDAC2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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