Article
MMP2 promoter polymorphism (C-1306T) and risk of recurrence in patients with hepatocellular carcinoma after transplantation.
Clinical genetics - 1 Mar 2008
Wu L M, Zhang F, Xie H Y, Xu X, Chen Q X, Yin S Y, Liu X C, Zhou L, Xu X B, Sun Y L, Zheng S S
Abstract excerpt
Genetic variants in matrix metalloproteinase (MMP) gene may influence the biological function of these enzymes and change their role in carcinogenesis and progression. The effect of MMP2 C-1306T and MMP9 C-1562T polymorphisms on genetic susceptibility has been investigated in various kinds of cancer. However, the relationship between these polymorphisms and risk of recurrence of hepatocellular carcinoma (HCC)...
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