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Article

Production of biologically active recombinant human factor H in Physcomitrella.

Plant biotechnology journal - 1 Apr 2011

Büttner-Mainik Annette, Parsons Juliana, Jérôme Hanna, Hartmann Andrea, Lamer Stephanie, Schaaf Andreas, Schlosser Andreas, Zipfel Peter F, Reski Ralf, Decker Eva L

Abstract excerpt

The human complement regulatory serum protein factor H (FH) is a promising future biopharmaceutical. Defects in the gene encoding FH are associated with human diseases like severe kidney and retinal disorders in the form of atypical haemolytic uremic syndrome (aHUS), membranoproliferative glomerulonephritis II (MPGN II) or age-related macular degeneration (AMD). There is a current need to apply intact full-length...

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PMID: 20723134
DOI: 10.1111/j.1467-7652.2010.00552.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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