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Article

Association of a common AGO1 variant with lung cancer risk: a two-stage case-control study.

Molecular carcinogenesis - 1 Oct 2010

Kim Jong-Sik, Choi Yi Young, Jin Guang, Kang Hyo-Gyoung, Choi Jin-Eun, Jeon Hyo-Sung, Lee Won-Kee, Kim Dong-Sun, Kim Chang Ho, Kim Young Jin, Son Ji-Woong, Jung Tae Hoon, Park Jae Yong

Abstract excerpt

Based on the important role of microRNA (miRNA) biosynthesis genes in carcinogenesis, we hypothesized that polymorphisms in the miRNA biosynthesis genes may modulate susceptibility to lung cancer. To test this hypothesis, we conducted a two-stage study to evaluate the associations between single nucleotide polymorphisms (SNPs) in the miRNA biosynthesis genes and the risk of lung cancer. In stage 1 of the study,...

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Source

Identifiers

PMID: 20721975
DOI: 10.1002/mc.20672

Genes

AGO1
AGO2
DGCR8
DROSHA
GEMIN4
RAN
XPO5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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