Article
Variant Analysis of miRNA Regulatory Genes in 35 Sporadic Lung Carcinoma Tumors.
Doklady. Biochemistry and biophysics - 1 Dec 2023
Bağcı Özkan, Özdemir Ebru Marzioğlu, Şanlıtürk Batuhan
Abstract excerpt
Lung cancer is one of the cancer types with the highest mortality worldwide. The most frequently mutated genes known to be clinically important in lung cancers are EGFR, BRAF, and KRAS genes. Therefore, the therapeutic agents developed are directed against variants that cause over-activation of the EGFR-KRAS-BRAF-BRAF-MEK/ERK signalling pathway. However, different responses of patients to Tyrosine Kinase...
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