Article
Establishment of the first World Health Organization International Genetic Reference Panel for quantitation of BCR-ABL mRNA
19 Aug 2010
Abstract excerpt
Serial quantitation of BCR-ABL mRNA levels is an important indicator of therapeutic response for patients with chronic myelogenous leukemia and Philadelphia chromosome-positive acute lymphoblastic leukemia, but there is substantial variation in the real-time quantitative polymerase chain reaction methodologies used by different testing laboratories. To help improve the comparability of results between centers we...
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