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Article

Laboratory testing in BCR‐ABL1‐like (Philadelphia‐like) B‐lymphoblastic leukemia/lymphoma

26 Apr 2018

Abstract excerpt

BCR-ABL1-like B-lymphoblastic leukemia/lymphoma (BCR-ABL1-like B-ALL), also known as Philadelphia-like (Ph-like) ALL, is a neoplasm of B-lineage lymphoblasts characterized by a pattern of gene expression similar to that of B-ALL with the BCR-ABL1 translocation but lacking the BCR-ABL1 fusion protein. The diagnosis of BCR-ABL1-like B-ALL is associated with a high rate of relapse and poor clinical outcomes. In...

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PMID: 29696694
DOI: 10.1002/ajh.25126

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