Article
Guidelines for the measurement of <i>BCR‐ABL1</i> transcripts in chronic myeloid leukaemia
8 Mar 2011
Abstract excerpt
Molecular testing for the BCR-ABL1 fusion gene by real time quantitative polymerase chain reaction (RT-qPCR) is the most sensitive routine approach for monitoring the response to therapy of patients with chronic myeloid leukaemia. In the context of tyrosine kinase inhibitor (TKI) therapy, the technique is most appropriate for patients who have achieved complete cytogenetic remission and can be used to define...
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