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Article

ST14 gene variant and decreased matriptase protein expression predict poor breast cancer survival.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Sept 2010

Kauppinen Jaana M, Kosma Veli-Matti, Soini Ylermi, Sironen Reijo, Nissinen Minna, Nykopp Timo K, Kärjä Vesa, Eskelinen Matti, Kataja Vesa, Mannermaa Arto

Abstract excerpt

BACKGROUND: Matriptase plays a role in carcinogenesis, but the role of its genetic variation or that of the hepatocyte growth factor activator inhibitor-1 (HAI-1) has not been evaluated. This study aimed to examine the genetic variation of matriptase (ST14 gene) and HAI-1 (SPINT1 gene) in breast...

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Source

Identifiers

PMID: 20716618
DOI: 10.1158/1055-9965.EPI-10-0418

Genes

SPINT1
IMPACT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20716618-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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