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Analysis of the relationships between oxidative stress, DNA damage and sperm vitality in a patient population: development of diagnostic criteria

17 Aug 2010

Abstract excerpt

BACKGROUND: DNA damage in human spermatozoa is known to be associated with a variety of adverse clinical outcomes affecting both reproductive efficiency and the health and wellbeing of the offspring. However, the origin of this damage, its biochemical nature and strategies for its amelioration, still await resolution. METHODS: Using novel methods to simultaneously assess DNA fragmentation (modified TUNEL assay),...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 20716559
DOI: 10.1093/humrep/deq214

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