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Article

Clinical significance of sperm DNA damage in assisted reproduction outcome

6 May 2010

Abstract excerpt

BACKGROUND: Sperm DNA damage shows great promise as a biomarker of infertility. The study aim is to determine the usefulness of DNA fragmentation (DF), including modified bases (MB), to predict assisted reproduction treatment (ART) outcomes. METHODS: DF in 360 couples (230 IVF and 130 ICSI) was measured by the alkaline Comet assay in semen and in sperm following density gradient centrifugation (DGC) and compared...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 20447937
DOI: 10.1093/humrep/deq103

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