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Article

Apoptosis and DNA damage in human spermatozoa

30 Aug 2010

Abstract excerpt

DNA damage is frequently encountered in spermatozoa of subfertile males and is correlated with a range of adverse clinical outcomes including impaired fertilization, disrupted preimplantation embryonic development, increased rates of miscarriage and an enhanced risk of disease in the progeny. The etiology of DNA fragmentation in human spermatozoa is closely correlated with the appearance of oxidative base adducts...

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Identifiers

PMID: 20802502
DOI: 10.1038/aja.2010.68

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