Article
Conserved role of unc-79 in ethanol responses in lightweight mutant mice.
PLoS genetics - 12 Aug 2010
Speca David J, Chihara Daisuke, Ashique Amir M, Bowers M Scott, Pierce-Shimomura Jonathan T, Lee Jungsoo, Rabbee Nusrat, Speed Terence P, Gularte Rodrigo J, Chitwood James, Medrano Juan F, Liao Mark, Sonner James M, Eger Edmond I, Peterson Andrew S, McIntire Steven L
Abstract excerpt
The mechanisms by which ethanol and inhaled anesthetics influence the nervous system are poorly understood. Here we describe the positional cloning and characterization of a new mouse mutation isolated in an N-ethyl-N-nitrosourea (ENU) forward mutagenesis screen for animals with enhanced locomoto...
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