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Article

[R248C FGFR3 mutation. Effect on cell growth, apoptosis and attachment in HaCaT keratinocytes].

Der Pathologe - 1 Oct 2010

Hafner C, Hartmann A

Abstract excerpt

Activating FGFR3 mutations have been identified in a variety of benign skin lesions (seborrheic keratosis, epidermal nevus, solar lentigo). However, the functional consequences of these mutations in the human epidermis are unknown. We therefore analyzed functional effects of the common R248C mutation in HaCaT keratinocytes. The cells were stably transduced with the R248C FGFR3 mutation or FGFR3-IIIb wildtype...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20711586
DOI: 10.1007/s00292-010-1332-z

Genes

FGFR3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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