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Article

Haplotypes of vitamin D receptor modulate the circulating levels of lead in exposed subjects.

Archives of toxicology - 1 Jan 2008

Rezende Vania B, Barbosa Fernando, Montenegro Marcelo F, Sandrim Valeria C, Gerlach Raquel F, Tanus-Santos Jose E

Abstract excerpt

Genetic factors influence whole blood lead (Pb-B) concentrations in lead exposed subjects. This study aimed at examining the combined effects (haplotype analysis) of three polymorphisms (BsmI, ApaI and FokI) in vitamin D receptor (VDR) gene on Pb-B and on the concentrations of lead in plasma (Pb-P), which is more relevant to lead toxicity, in 150 environmentally exposed subjects. Genotypes were determined by...

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Share to Deoxyribonucleases, Type II Site-Specific
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Receptors, Calcitriol

Share to Reverse Transcriptase Polymerase Chain Reaction

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Source

Identifiers

PMID: 17701399
DOI: 10.1007/s00204-007-0231-4

Genes

VDR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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