Article
Genetic variation and antioxidant response gene expression in the bronchial airway epithelium of smokers at risk for lung cancer.
PloS one - 3 Aug 2010
Wang Xuting, Chorley Brian N, Pittman Gary S, Kleeberger Steven R, Brothers John, Liu Gang, Spira Avrum, Bell Douglas A
Abstract excerpt
Prior microarray studies of smokers at high risk for lung cancer have demonstrated that heterogeneity in bronchial airway epithelial cell gene expression response to smoking can serve as an early diagnostic biomarker for lung cancer. As a first step in applying functional genomic analysis to population studies, we have examined the relationship between gene expression variation and genetic variation in a central...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.