Article
Transcriptomic epidemiology of smoking: the effect of smoking on gene expression in lymphocytes.
BMC medical genomics - 15 Jul 2010
Charlesworth Jac C, Curran Joanne E, Johnson Matthew P, Göring Harald Hh, Dyer Thomas D, Diego Vincent P, Kent Jack W, Mahaney Michael C, Almasy Laura, MacCluer Jean W, Moses Eric K, Blangero John
Abstract excerpt
BACKGROUND: This investigation offers insights into system-wide pathological processes induced in response to cigarette smoke exposure by determining its influences at the gene expression level. METHODS: We obtained genome-wide quantitative transcriptional profiles from 1,240 individuals from the...
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