Article
Genomic identification of significant targets in ciliochoroidal melanoma.
Investigative ophthalmology & visual science - 9 May 2011
McCannel Tara A, Burgess Barry L, Nelson Stanley F, Eskin Ascia, Straatsma Bradley R
Abstract excerpt
PURPOSE: To identify genomic targets for ciliochoroidal melanoma diagnosis, prognosis, and therapy. METHODS: Fifty-eight ciliochoroidal melanomas were analyzed by high-resolution, genome-wide, single nucleotide polymorphism (SNP) mapping arrays. The 58 SNP arrays were compared to 48 HapMap normals representing both sexes and assessed with a systematic statistical method, Genomic Identification of Significant...
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