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Article

Bottlenecks and the maintenance of minor genotypes during the life cycle of Trypanosoma brucei.

PLoS pathogens - 29 Jul 2010

Oberle Michael, Balmer Oliver, Brun Reto, Roditi Isabel

Abstract excerpt

African trypanosomes are digenetic parasites that undergo part of their developmental cycle in mammals and part in tsetse flies. We established a novel technique to monitor the population dynamics of Trypanosoma brucei throughout its life cycle while minimising the confounding factors of strain differences or variation in fitness. Clones derived from a single trypanosome were tagged with short synthetic DNA...

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Identifiers

PMID: 20686656
DOI: 10.1371/journal.ppat.1001023
PMCID: PMC2912391

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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