Article
Neutralization activity in a geographically diverse East London cohort of human immunodeficiency virus type 1-infected patients: clade C infection results in a stronger and broader humoral immune response than clade B infection.
The Journal of general virology - 1 Nov 2010
Dreja Hanna, O'Sullivan Eithne, Pade Corinna, Greene Kelli M, Gao Hongmei, Aubin Keith, Hand James, Isaksen Are, D'Souza Carl, Leber Werner, Montefiori David, Seaman Michael S, Anderson Jane, Orkin Chloe, McKnight Aine
Abstract excerpt
The array of human immunodeficiency virus (HIV) subtypes encountered in East London, an area long associated with migration, is unusually heterogeneous, reflecting the diverse geographical origins of the population. In this study it was shown that viral subtypes or clades infecting a sample of HIV type 1 (HIV-1)-positive individuals in East London reflect the global pandemic. The authors studied the humoral...
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