Article
Altered matrix production in the distal airways of individuals with asthma.
Thorax - 1 Aug 2010
Nihlberg Kristian, Andersson-Sjöland Annika, Tufvesson Ellen, Erjefält Jonas S, Bjermer Leif, Westergren-Thorsson Gunilla
Abstract excerpt
BACKGROUND AND AIMS: Although increasing evidence suggests involvement of the distal airway in all stages of asthma, it is not known whether structural changes (defined as airway remodelling) occur in the distal airways of subjects with mild asthma and those with atopy. The aim of this study was to compare control subjects and those with mild asthma in relation to fibroblast phenotypes and remodelling in central...
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