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Article

Comprehensive analysis of genes involved in the malignancy of gastrointestinal stromal tumors.

Anticancer research - 1 Jul 2010

Tsumuraya Miyako, Kato Hiroyuki, Miyachi Kazuhito, Sasaki Kinro, Tsubaki Masahiro, Akimoto Kazumi, Sunagawa Masakatsu

Abstract excerpt

BACKGROUND: During tumorigenesis of gastrointestinal stromal tumors (GISTs), the most frequent changes are reported to be gain-of-function mutations in the C-KIT proto-oncogene. However, we speculated that additional genetic alterations are required for the progression of GISTs. PATIENTS AND METHODS: Using 15 cases diagnosed with GISTs, we searched for novel indicator genes by microarray analyses using an Oligo...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20683002

Genes

KIT
ACTB
RBL2
RHOA
SHC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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