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Article

Gene methylation of SFRP2, P16, DAPK1, HIC1, and MGMT and KRAS mutations in sporadic colorectal cancer.

Cancer genetics and cytogenetics - 1 Sept 2010

Pehlivan Sacide, Artac Mehmet, Sever Tugce, Bozcuk Hakan, Kilincarslan Can, Pehlivan Mustafa

Abstract excerpt

The aim of this study was to investigate the methylation of the SFRP2, P16, DAPK1, HIC1, and MGMT genes, as well as the mutation of amino acid codons 12 and 13 of the KRAS gene in normal and tumor tissue DNA of patients diagnosed with sporadic colorectal cancer (SCRC). The methylation of gene regions and the KRAS mutations of normal (N) and tumor tissue (T) DNA obtained from 17 patients diagnosed with SCRC and 20...

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Source

Identifiers

PMID: 20682398
DOI: 10.1016/j.cancergencyto.2010.05.019

Genes

KRAS
DAPK1
HIC1
MGMT
SFRP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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