Article
Distinct subregions of Swi1 manifest striking differences in prion transmission and SWI/SNF function.
Molecular and cellular biology - 1 Oct 2010
Du Zhiqiang, Crow Emily T, Kang Hyun Seok, Li Liming
Abstract excerpt
We have recently reported that the yeast chromatin-remodeling factor Swi1 can exist as a prion, [SWI(+)], demonstrating a link between prionogenesis and global transcriptional regulation. To shed light on how the Swi1 conformational switch influences Swi1 function and to define the sequence and s...
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