Characterization of the<i>ebp_fm</i>pilus-encoding operon of<i>Enterococcus faecium</i>and its role in biofilm formation and virulence in a murine model of urinary tract infection

Abstract excerpt

We recently identified 15 genes encoding putative surface proteins with features of MSCRAMMs and/or pili in the Enterococcus faecium TX0016 (DO) genome, including four predicted pilus-encoding gene clusters; we also demonstrated that one of these, ebpABC(fm), is transcribed as an operon, that its putative major pilus subunit, EbpC(fm) (also called pilB), is polymerized into high molecular weight complexes, and...

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