Article
Enterococcus faecalis rnjB is required for pilin gene expression and biofilm formation.
Journal of bacteriology - 1 Oct 2010
Gao Peng, Pinkston Kenneth L, Nallapareddy Sreedhar R, van Hoof Ambro, Murray Barbara E, Harvey Barrett R
Abstract excerpt
Pili in Gram-positive bacteria play a major role in the colonization of host tissue and in the development of biofilms. They are promising candidates for vaccines or drug targets since they are highly immunogenic and share common structural and functional features among various Gram-positive pathogens. Numerous publications have helped build a detailed understanding of pilus surface assembly, yet regulation of...
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