Article
Conservation of Ebp-type pilus genes among Enterococci and demonstration of their role in adherence of Enterococcus faecalis to human platelets.
Infection and immunity - 1 Jul 2011
Nallapareddy Sreedhar R, Sillanpää Jouko, Mitchell Jennifer, Singh Kavindra V, Chowdhury Shahreen A, Weinstock George M, Sullam Paul M, Murray Barbara E
Abstract excerpt
Ebp are endocarditis- and biofilm-associated pili of Enterococcus faecalis that are also important in experimental urinary tract infections (UTIs). Our analyses, using available genomes, found that the ebp locus is unique to enterococci. In E. faecalis, the ebp locus is very highly conserved and only 1/473 E. faecalis isolates tested lacked ebpABC, while only 1.2% had the bee pilus locus. No other pilus-encoding...
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