Pleiotropic Regulation of Virulence Genes in Streptococcus mutans by the Conserved Small Protein SprV.

doi:10.1128/JB.00847-16

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Article

Pleiotropic Regulation of Virulence Genes in Streptococcus mutans by the Conserved Small Protein SprV.

Journal of bacteriology - 15 Apr 2017

Shankar Manoharan, Hossain Mohammad S, Biswas Indranil

Abstract excerpt

Streptococcus mutans, an oral pathogen associated with dental caries, colonizes tooth surfaces as polymicrobial biofilms known as dental plaque. S. mutans expresses several virulence factors that allow the organism to tolerate environmental fluctuations and compete with other microorganisms. We recently identified a small hypothetical protein (90 amino acids) essential for the normal growth of the bacterium....

Topics

Bacterial Proteins
Biofilms
Conserved Sequence
DNA, Bacterial
Gene Expression Regulation, Bacterial
Genome, Bacterial
Mutation
Streptococcus mutans
Stress, Physiological
Virulence
Virulence Factors

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Identifiers

PMID: 28167518
DOI: 10.1128/JB.00847-16
PMCID: PMC5370425

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