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Article

MET receptor sequence variants R970C and T992I lack transforming capacity.

Cancer research - 1 Aug 2010

Tyner Jeffrey W, Fletcher Luke B, Wang Ellen Q, Yang Wayne F, Rutenberg-Schoenberg Michael L, Beadling Carol, Mori Motomi, Heinrich Michael C, Deininger Michael W, Druker Brian J, Loriaux Marc M

Abstract excerpt

High-throughput sequencing promises to accelerate the discovery of sequence variants, but distinguishing oncogenic mutations from irrelevant "passenger" mutations remains a major challenge. Here we present an analysis of two sequence variants of the MET receptor (hepatocyte growth factor receptor...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20670955
DOI: 10.1158/0008-5472.CAN-10-0429
PMCID: PMC2913476

Genes

MET

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20670955-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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